Tuesday, August 25, 2009

Sleep - Jet Lag - Dr Yacoob Omar Carrim

Sleep - Jet Lag and other circadian rhytm disorders

Other Circadian disorders
  • Shift work sleep disorder
  • circadian sleep-wake disorder of blindness
Symptoms
  • Disrupted female mestruation cycle - female flight attendents
  • Meals eaten out of phase - result in inappropriate pancreatic and metabolic responses and may be long term risk factors for heart disease
  • Life span can be shorterned by phase shifting
SWSD - shiftworkers - sleep problems, GIT problems, metabolic syndrome, heart disease and cancer

Suprachiasmic nucleus of the hypothalamus
  • Central pacemaker
Melatonin, light, body temperature

Management:
Sleep hygine
  • reduce noise, unwanted stimuli, earplugs, eye patches
  • avoid alcohol and caffine
  • jet leg diet - carbs at night for seratonin synthasis and protien in the day - thyrosine, catacholamine production
  • Naps
  • Hypnotic agents - short acting "Z" drugs
  • Light - Lab studies - 460 to 465 nm (Blue); field studies
Melatonin: produced at night for the duration of the night. ? effect on reproduction

Dr Yacoob Omar Carrim
zasleep@gmail.com




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