By Dr Carrim at Dec 7, 2009 3:12 PM IST
Obstructive Sleep Apnoea has a number of effects - amongst others sleep fragmentation and hypoxia. These effects initially stimulate leptin, Il6 and TNF from fat cells. Leptin resistance develops thereafter creating DIET RESISTANT FAT. This DIET RESISTANT FAT - is as the name suggest resistant to changes in diet.
Successful management with a CPAP would reduce the leptin resistance and allow the patient to loose weight.
Thanks
Dr Y Carrim
Sleep Specialist
South Africa
+27715216757
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